Biomodelado virtual de una estructura biológica: la córnea humana

Abstract

The cornea is the most important part of

the anterior segment of the human eye. In a

natural scenario, the tissue that forms part

of the corneal architecture presents a stable

geometrical morphology, while in a pathological

scenario a morphological alteration that

affects to the geometry of its architecture is

detected. The use of virtual models of biologic

structures in the field of Biomedical Engineering

has been demonstrated to be very useful in

clinical practice for diagnosis and surgical

reconstruction. This paper presents the virtual

modelling of the human cornea as a technique

for the diagnosis of the corneal pathology

named keratoconus. After generating the virtual

model of the cornea, several geometric variables

are then extracted and analyzed, permitting to

differentiate between healthy and keratoconic

corneas. The obtained results have been clinically

validated and demonstrate the functionality

of the methodology applied, being possible to

extend this methodology to other geometric

variables.